Metabolism of 17α-Ethynyl Estradiol and 17β-Estradiol in Vivo
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چکیده
منابع مشابه
Simultaneous Degradation of Estrone, 17β-Estradiol and 17α-Ethinyl Estradiol in an Aqueous UV/H2O2 System
UV/H₂O₂, which is an advanced treatment technology used to reduce multiple contaminants, is effective in potable water treatment. Simultaneous degradation effects and kinetics of three types of coexisting micropollutant estrogens (steroid estrogens, SEs), including estrone (E1), 17β-estradiol (E2) and 17α-ethinyl estradiol (EE2), in deionized water were studied. Experiments were carried out wit...
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Sexually mature pigs are known to possess high concentrations of testicular steroids, which have been shown to change the activities of cytochrome P450 in vitro. The aim of the present study was to evaluate the regulation of CYP1A and CYP2E1 activity by the steroids dihydrotestosterone (DHT), 3β-androstenol, 17β-estradiol and 17α-estradiol. Catalytic activities of 7-ethoxyresorufin O-deethylase...
متن کاملComparative biological effects and potency of 17α- and 17β-estradiol in fathead minnows.
17β-Estradiol is the most potent natural estrogen commonly found in anthropogenically altered environments and has been the focus of many toxicological laboratory studies. However, fewer aquatic toxicological data on the effects of 17α-estradiol, a diastereoisomer of 17β-estradiol, exists in the literature even though it has been found in the aquatic environment, sometimes at higher concentrati...
متن کاملMacromolecular prodrugs. XIII. Hydrosoluble conjugates of 17β-estradiol and estradiol-17β-valerate with polyaspartamide polymer.
Two hydrosoluble conjugates of 17β-estradiol (ED) and estradiol-17β-valerate (EV) with polyaspartamide polymer were prepared and characterized. ED and EV were first chemically modified and bound to poly[α,β-(N-2-hydroxyethyl-DL-aspartamide)]-poly[α,β-(N-2-aminoethyl-DL-aspartamide)] (PAHA), a hydrosoluble polyaspartamide-type copolymer bearing both hydroxyl and amino groups. ED was first conver...
متن کاملImmunomodulation by 17β-Estradiol in bivalve hemocytes
In mammals, estrogens have both doseand cell-type specific effects on immune cells and may act as pro-inflammatory and anti-inflammatory stimuli depending on the setting. Evidence has been provided that in the bivalve mollusc Mytilus the natural estrogen 17β-estradiol (E2) can affect neuro-immune functions. In this work the immunomodulatory role of E2 in Mytilus hemocytes, the cells responsible...
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ژورنال
عنوان ژورنال: Folia Endocrinologica Japonica
سال: 1969
ISSN: 0029-0661
DOI: 10.1507/endocrine1927.44.10_1153